©2023 – Seeq Corporation©2023 – Seeq Corporation

Solving Complex Pharma Challenges with Intelligent Analytics: A Seeq AI Deep Dive

Asif Hassan, Tatum O’Kennedy, Andres Barbaro

©2024 – Seeq Corporation | 2©2024 – Seeq Corporation | 2©2024 – Seeq Corporation | 2

Meet the Presenters

Andres Barbaro Asif Hassan Tatum O’Kennedy

©2024 – Seeq Corporation | 3©2024 – Seeq Corporation | 3©2024 – Seeq Corporation | 3

Agenda

1

2

3

4

INTRODUCTION

AI OVERVIEW

PHARMA DAY IN THE LIFE &

DEMO

ROADMAP & WRAP-UP

5

Q&A

©2024 – Seeq Corporation | 5©2024 – Seeq Corporation | 5 For a complete list of supported connectors, visit support.seeq.com

Architecture Overview

https://support.seeq.com/space/KB/1666908368/Supported+Connectors

©2023 – Seeq Corporation©2023 – Seeq Corporation

AI at Seeq: A Deep Dive into Optimizing your Pharmaceutical Insights

©2024 – Seeq Corporation | 9©2024 – Seeq Corporation | 9

It’s all about enabling and scaling the SMEs

Inform Learn Faster

Accelerate Do More

Scale Deeper Insights

User Experience

Our goal is to help every industry expert be curious, learn faster, do more, and create maximum value to their stakeholders.

Seeq AI provides an analytics helper to your team, giving your experts a platform to grow and scale themselves, their team, and the entire organization.

Capturing your thought process, your insights, your results.

Forming more SMEs along the way.

©2024 – Seeq Corporation | 10©2024 – Seeq Corporation | 10

Learn Faster and Do More…

A

B

…with a natural language user interface and

copilot assistance

Scale Your Expertise…

…with automated, enterprise decision

support

©2024 – Seeq Corporation | 11©2024 – Seeq Corporation | 11

Seeq Platform and AI Assistant

General Help

RELEASED

RELEASED

RELEASED

Retrieve information and guide the user.

RELEASED

©2024 – Seeq Corporation | 12©2024 – Seeq Corporation | 12©2024 – Seeq Corporation | 12

Seeq AI Assistant Agents

Formula Data LabGeneralist Generate and implement analytics

Generate and execute python code, debug and explain code purpose

Provide general answers / assistance / actions across the platform

Accessible and adapted for any Seeq workflow

Action

Create new items and modify the display

How do I identify anomalies in my batch production data?

Generate a formula to calculate a normalized yield for each batch, accounting for theoretical yield and actual production.

Help me create a Multi-Dimensional Batch Comparison Sankey Diagram.

Smooth reactor temperature signals and create a tabular view of the maximums.

©2024 – Seeq Corporation | 13©2024 – Seeq Corporation | 13

Learn Faster and Do More…

A

B

…with a natural language user interface and

copilot assistance

Scale Your Expertise…

…with automated, enterprise decision

support

THE INSIGHTS PYRAMID

Signals, Conditions, Scalars

THE INSIGHTS PYRAMID

Create a condition to detect when pump 123 is consuming more than 95kW and call it “Pump High Load.”

Signals, Conditions, Scalars

Worksheets, Dashboards, Documents, Journals

THE INSIGHTS PYRAMID

Create a condition to detect when pump 123 is consuming more than 95kW and call it “Pump High Load.”

Visualize pump inlet and outlet pressures and associated power consumption.

Signals, Conditions, Scalars

Worksheets, Dashboards, Documents, Journals

Models

THE INSIGHTS PYRAMID

Create a condition to detect when pump 123 is consuming more than 95kW and call it “Pump High Load.”

Visualize pump inlet and outlet pressures and associated power consumption.

Apply the pump model to every one of my pumps made by Flowserve.

Signals, Conditions, Scalars

Worksheets, Dashboards, Documents, Journals

Models

Vantage Rooms

THE INSIGHTS PYRAMID

Create a condition to detect when pump 123 is consuming more than 95kW and call it “Pump High Load.”

Visualize pump inlet and outlet pressures and associated power consumption.

Apply the pump model to every one of my pumps made by Flowserve.

Was there any downtime related to material shortage yesterday on the Acme product lines?

Signals, Conditions, Scalars

Worksheets, Dashboards, Documents, Journals

Models

Vantage Rooms

AI Agents

THE INSIGHTS PYRAMID

Create a condition to detect when pump 123 is consuming more than 95kW and call it “Pump High Load.”

Visualize pump inlet and outlet pressures and associated power consumption.

Apply the pump model to every one of my pumps made by Flowserve.

Was there any downtime related to material shortage yesterday on the Acme product lines?

Compare operations by batch, site and shift for last six months.

©2023 – Seeq Corporation©2023 – Seeq Corporation

A Day in the Life: Pharmaceutical Manufacturing

2121 ©2024 – Seeq Corporation

Question to you!

©2024 – Seeq Corporation | 22©2024 – Seeq Corporation | 22©2024 – Seeq Corporation | 22

Key Challenges with Deviation Investigation

Resource Allocation Inefficiencies

©2024 – Seeq Corporation | 23©2024 – Seeq Corporation | 23©2024 – Seeq Corporation | 23

Key Challenges with Deviation Investigation

Manual & Time- Intensive Processes

Resource Allocation Inefficiencies

©2024 – Seeq Corporation | 24©2024 – Seeq Corporation | 24©2024 – Seeq Corporation | 24

Key Challenges with Deviation Investigation

Manual & Time- Intensive Processes

Limited Real-Time Visibility &

Contextualization

Resource Allocation Inefficiencies

©2024 – Seeq Corporation | 25©2024 – Seeq Corporation | 25©2024 – Seeq Corporation | 25

Key Challenges with Deviation Investigation

Manual & Time- Intensive Processes

Reactive Culture

Limited Real-Time Visibility &

Contextualization

Resource Allocation Inefficiencies

©2024 – Seeq Corporation | 26©2024 – Seeq Corporation | 26©2024 – Seeq Corporation | 26

Key Challenges with Deviation Investigation

Manual & Time- Intensive Processes

Reactive Culture

Limited Real-Time Visibility &

Contextualization

Documentation Burden

Resource Allocation Inefficiencies

©2024 – Seeq Corporation | 27©2024 – Seeq Corporation | 27©2024 – Seeq Corporation | 27

Transforming Deviation Management

Real-Time Detection & Flagging

©2024 – Seeq Corporation | 28©2024 – Seeq Corporation | 28©2024 – Seeq Corporation | 28

Transforming Deviation Management

Real-Time Detection & Flagging

Intelligent Investigation

©2024 – Seeq Corporation | 29©2024 – Seeq Corporation | 29©2024 – Seeq Corporation | 29

Transforming Deviation Management

Real-Time Detection & Flagging

Intelligent Investigation

AI-Powered Reporting

©2024 – Seeq Corporation | 30©2024 – Seeq Corporation | 30©2024 – Seeq Corporation | 30

Transforming Deviation Management

Real-Time Detection & Flagging

Intelligent Investigation

AI-Powered Reporting

Secure Review & Compliance

3131

Operator

©2024 – Seeq Corporation

Responsibilities • Real-time process

monitoring • Support Deviation

investigation

Needs • Simple, actionable

dashboards • Exception-based

reporting • Method of Flagging to

Engineering

3232

MSAT / Manufacturing / Process Engineer

©2024 – Seeq Corporation

Responsibilities • Deviation

Investigation • Regulatory

Compliance

Needs • Access to process and

quality data • Advanced Data

Analytics & Drilldown • Regulatory Reporting

3333

Head of Quality Assurance

©2024 – Seeq Corporation

Responsibilities • Regulatory/Procedural

Compliance • Deviation

Management

Needs • Comprehensive

Reporting • Trend Analysis

3434

Director of Operations

©2024 – Seeq Corporation

Responsibilities • Performance

Benchmarking • Site-Wide Monitoring

Needs • Executive Dashboards • Site-Wide Reporting

©2024 – Seeq Corporation | 35©2024 – Seeq Corporation | 35©2024 – Seeq Corporation | 35

Seeq AI Enhanced Enterprise Workflow

Process Dashboard Monitoring

Vantage Event

Flagging for Targeted Personas

Workbench Investigation

& Analysis Locking

Vantage Review

Flagging & Reporting

Operations Operations / MSAT MSAT QA / Operations

SCALED ACROSS ASSETS

3636

Demonstration

©2024 – Seeq Corporation

©2024 – Seeq Corporation | 37©2024 – Seeq Corporation | 37©2024 – Seeq Corporation | 37

Seeq AI Enhanced Enterprise Workflow

Process Dashboard Monitoring

Vantage Event

Flagging for Targeted Personas

Workbench Investigation

& Analysis Locking

Vantage Review

Flagging & Reporting

Operations Operations / MSAT MSAT QA / Operations

SCALED ACROSS ASSETS

©2024 – Seeq Corporation | 38©2024 – Seeq Corporation | 38©2024 – Seeq Corporation | 38

Seeq AI Enhanced Enterprise Workflow Benefits

• Reduction of manual and laborious processes through a streamlined and automated Seeq workflow.

• Empowers operational personnel with real time access to data from multiple sources and equipping them with power analytical tools for RCA.

• Valuable process knowledge captured in Seeq through triaging and contextualization of critical process events at scale by operators and SME’s through Seeq Vantage

• Accelerated time to value through AI-enhanced insights and report generation.

We’re building Industrial AI to go ALL-IN

Everyone, All levels

Your Insights, Shared

Go Further

We’re building Industrial AI for you

8989

Seeq AI Agent Types

©2024 – Seeq Corporation

Chat and Action: Experts learn faster and do more in Seeq. Launched Feb 2024.

Expert Insights: Experts instruct ”Agent Q” to automate the generation of insights for their workflows. Actively working with customers via Lighthouse Engagements.

Knowledge Miners: background AI agents that dig the “Seeq knowledge mine” autonomously to to build memories and surface relevant context for users. Building.

Enterprise Executive Insights: Answer top-level business questions about process and manufacturing operations. Building.

©2024 – Seeq Corporation | 90©2024 – Seeq Corporation | 90

Agentic AI for Experts Insights

Quality Deviations

Operating Cost

Time to Identify Anomalies

Unplanned Downtime

Time to Issue ResolutionLOB Leader

Engineer

Plant Manager

Ops / Mfg Leader

©2024 – Seeq Corporation | 91©2024 – Seeq Corporation | 91

In-meeting demo #1 by Andres Barbaro,

VP Software Engineering

Agentic AI for Experts Insights

Quality Deviations

Operating Cost

Time to Identify Anomalies

Unplanned Downtime

Time to Issue ResolutionLOB Leader

Engineer

Plant Manager

Ops / Mfg Leader

92

©2024 – Seeq Corporation | 95©2024 – Seeq Corporation | 95©2024 – Seeq Corporation | 95

AI Roadmap (Andres)

©2024 – Seeq Corporation | 96©2024 – Seeq Corporation | 96

Sustained Impact

Building Blocks to Enterprise Value in Seeq

Rapid Insights & ROI

Scaled and Automated

• Generative AI Enabled Experts • Extensible To Accelerate BI and ML • Purpose-Built for Time Series Analytics

• SME Context at Scale • Monitoring by Exception • Automated Operational Surveillance

979797979797 ©2024 – Seeq Corporation

Why Seeq for Pharma Manufacturing?

•GMP-Ready Platform

989898989898 ©2024 – Seeq Corporation

Why Seeq for Pharma Manufacturing?

•GMP-Ready Platform

•Analytics at Your Fingertips

999999999999 ©2024 – Seeq Corporation

Why Seeq for Pharma Manufacturing?

•GMP-Ready Platform

•Analytics at Your Fingertips

•GenAI-Accelerated Insights

100100100100100100 ©2024 – Seeq Corporation

Why Seeq for Pharma Manufacturing?

•GMP-Ready Platform

•Analytics at Your Fingertips

•GenAI-Accelerated Insights

•Operational Flexibility

©2024 – Seeq Corporation | 101©2024 – Seeq Corporation | 101©2024 – Seeq Corporation | 101

Thank You!

Default Section Slide 1: Solving Complex Pharma Challenges with Intelligent Analytics: A Seeq AI Deep Dive Slide 2: Meet the Presenters Slide 3: Agenda Slide 5: Architecture Overview Slide 8: AI at Seeq: A Deep Dive into Optimizing your Pharmaceutical Insights Slide 9: It’s all about enabling and scaling the SMEs Slide 10 Slide 11: Seeq Platform and AI Assistant Slide 12: Seeq AI Assistant Agents Slide 13 Slide 14: The Insights Pyramid Slide 15: The Insights Pyramid Slide 16: The Insights Pyramid Slide 17: The Insights Pyramid Slide 18: The Insights Pyramid Slide 19: The Insights Pyramid Slide 20: A Day in the Life: Pharmaceutical Manufacturing Slide 21: Question to you! Slide 22: Key Challenges with Deviation Investigation Slide 23: Key Challenges with Deviation Investigation Slide 24: Key Challenges with Deviation Investigation Slide 25: Key Challenges with Deviation Investigation Slide 26: Key Challenges with Deviation Investigation Slide 27: Transforming Deviation Management Slide 28: Transforming Deviation Management Slide 29: Transforming Deviation Management Slide 30: Transforming Deviation Management Slide 31: Operator Slide 32: MSAT / Manufacturing / Process Engineer Slide 33: Head of Quality Assurance Slide 34: Director of Operations Slide 35: Seeq AI Enhanced Enterprise Workflow Slide 36: Demonstration Slide 37: Seeq AI Enhanced Enterprise Workflow Slide 38: Seeq AI Enhanced Enterprise Workflow Benefits Slide 39: We’re building Industrial AI to go ALL-IN Slide 40: Everyone, All levels Slide 41 Slide 42 Slide 43 Slide 44 Slide 45 Slide 46 Slide 47 Slide 48 Slide 50 Slide 51 Slide 52 Slide 53 Slide 54: Your Insights, Shared Slide 56 Slide 57 Slide 58 Slide 59 Slide 60 Slide 61 Slide 62 Slide 63 Slide 64 Slide 65 Slide 66 Slide 67 Slide 68 Slide 69 Slide 70 Slide 71: Go Further Slide 72 Slide 73 Slide 74 Slide 75 Slide 76 Slide 77 Slide 78 Slide 79 Slide 80 Slide 81 Slide 82 Slide 83 Slide 84 Slide 85 Slide 86 Slide 87 Slide 88: We’re building Industrial AI for you Slide 89: Seeq AI Agent Types Slide 90: Agentic AI for Experts Insights Slide 91: Agentic AI for Experts Insights Slide 92

Resources Slide 95: AI Roadmap (Andres) Slide 96: Building Blocks to Enterprise Value in Seeq Slide 97: Why Seeq for Pharma Manufacturing? Slide 98: Why Seeq for Pharma Manufacturing? Slide 99: Why Seeq for Pharma Manufacturing? Slide 100: Why Seeq for Pharma Manufacturing? Slide 101: Thank You!